I have a Panasonic AS650 TV which plays all videos bar a couple of AVI formats - Divx & JPEG/MJPG ( from a wildlife camera ).

Because of the MJPG videos I had to switch on transcoding. Having done this numerous MKV videos suddenly needed transcoding to MPEGTS format whereas they were fine before.

Turned out that the audio content was 640kbps where the max bitrate in the prf files is 448kbps. Simply changing that max solved that problem.

This was in the PanasonicViera2013.prf and above. BUT no doubt a general issue though.

Before I solved this I had just installed 5.1.1.0 (over 4.1.3.0) so I thought I'd try the other prfs that might match my TV. There are 2 new files in DeviceProfiles - PanasonicViera2015UHD & PanasonicViera2016UHD but only the 2015 shows up in the dropdown options for my TV. Turns out that both have the same GUID & title.
Having changed the title & GUID in the 2016 version so it now functions correctly.

Both the above issues need correcting.