It sounds like your Windows 10 firewall is either blocking DLNA/UPnP communication and/or blocking Mezzmo.exe & MezzmoMediaServer.exe from accessing your home network. Try this: Go to the Media Server Settings dialog in Mezzmo and rename your Mezzmo server (e.g. "Mezzmo Win 10"). Click OK to save your name change. This forces your Mezzmo server to re-registered as a Windows service on your computer and it may clear up any blocking that may be appearing. Let us know how you go.